Dr Brown works on a variety of vector-borne and zoonotic diseases with an effort to better understand and thus control human disease risk. The complex nature of these systems require blending field collections, ecological assessment, laboratory experiments, epidemiological analysis, spatial statistics, remote sensing, geographic information systems, and computer-based modeling in order to develop a more comprehensive view of disease dynamics. Current research areas include: West Nile virus, dengue, canine heartworm, valley fever, spatial epidemiology, and climate change.
Sedda, L., Brown, H.E., Purse, B.V., Burgin, L., Gloster, J., Rogers, D.J. “A new algorithm quantifies the roles of wind and midge flight activity in the bluetongue epizootic in North-West Europe.” Proceedings of the Royal Society Biology. 8 February 2012. doi:10.1098/rspb.2011.2555.
Brown, H.E., Levy, C.E., Enscore, R.E., Schriefer, M.E., DeLiberto, T.J., Gage, K.L., Eisen, R.J. “Annual seroprevalence of Yersinia pestis in coyotes as predictors of interannual variation in reports of human plague cases in Arizona, USA.” Vector-Borne and Zoonotic Diseases. 2011 Jul 14. 11(11): 1439-1446.
Brown, H.E., Ettestad, P., Reynolds, P., Brown, T., Hatton, E., Holmes, J., Glass, G., Gage, K., and Eisen, R. “Climatic predictors of the intra- and inter-annual distributions of plague cases in New Mexico based on 29 years of animal-based surveillance data.” American Journal of Tropical Medicine and Hygiene. 2010, 82(1), p. 95-102.
Hartemink, N., Purse, B.V., Meiswinkel, R., Brown, H.E., de Koeijer, A., Elbers, A.R., Jan Boender, G., Rogers, D.J., Heesterbeek, H. “Mapping the basic reproduction number (R0) for vector-borne diseases: A case study on bluetongue virus.” Epidemics. 2009, 3(1), p. 153-161.
Purse, B.V., Brown, H.E., Harrup, L., PPC Mertens and Rogers D.J., “Invasion of bluetongue and other orbivirus infections into Europe: the role of biological and climatic processes.” Revue scientifique et technique. 2008, 27(2), p. 427-442.
Brown, H.E., Childs, J.E., Diuk-Wasser, M.A., and Fish, D. “Ecological factors associated with West Nile virus transmission, northeastern United States.” Emerging Infectious Diseases. 2008, 14(10), p. 1539-1545.
Brown, H.E., Diuk-Wasser, M.A., Guan, Y., Caskey, S., and Fish, D. “Comparison of three satellite sensors at three spatial scales to predict larval mosquito presence in CT Wetlands.” Remote Sensing of the Environment. 2008, 112(5), p. 2301-2308.
Diuk-Wasser, M.A., Brown, H.E., Andreadis, T.G., and Fish, D. “Modeling the spatial distribution of mosquito vectors for West Nile virus in Connecticut, USA.” Vector-Borne and Zoonotic Diseases. 2006, 6(3), p. 283-95. Book Chapters and Reports
Ernst, K.C., Morin, C., Brown, H.E. (2014) Extreme Weather Events and Vector-borne Diseases. in Public Health in Natural Disasters: Nutrition, Food, Remediation and Preparation (eds) Ronald Ross Watson, Joseph A. Tabor, John E. Ehiri, and Victor R. Preedy: Wageningen Academic Publishers. In Press
Brown, H.E., Comrie, A.C., Tamerius, J., Khan, M., Tabor, J.A., Galgiani, J.N. “Climate, windstorms, and the risk of valley fever (Coccidioidomycosis)” in Institute of Medicine. The influence of Global Environmental Change on Infectious Disease Dynamics: Workshop Summary. Washington, DC: The National Academies Press, 2014 “Appendix A12: Pages 266 – 282.
Brown, H.E., Comrie, A., Drechsler, D., Barker, C.M., Basu, R., Brown, T., Gershunov, A., Kilpatrick, A.M., Reisen, W.K., and Ruddell, D. Review Editor: English, P. Health Effects of Climate Change in the Southwest. Chapter 15, in: Assessment of Climate Change in the Southwest United States: a Technical Report Prepared for the U.S. National Climate Assessment. A report by the Southwest Climate Alliance [Garfin, G., Jardine, A., Merideth, R., Black, M., and Overpeck, J. (eds.)]. Tucson, AZ: Southwest Climate Alliance.
Hudspeth, W., Reisen, W.K., Barker, C.M., Kramer, V., Caian, M., Craciunescu, V., Brown, H.E., Comrie, A.C., Zelicoff, A., Ward, T.G., Ragain, R.M., Simpson, G., Stanhope, W., Kass-Hout, T.A., Scharl, A., Sonricker, A.L., Brownstein, J.S. to “Chapter 10: Information Support Systems” in Environmental Tracking for Public Health Surveillance. Morain, S.A. and Budge, A.M.(eds). 2012, Taylor & Francis Group, London.